HOMETOWN
Shanghai, China

EDUCATION & MEDICAL TRAINING
Nanjing Medical University – Nanjing, China

FELLOWSHIP
GI/Liver – UCLA

EXTRACURRICULAR ACTIVITIES
Exercising, basketball, biking, hiking, backpacking, fishing, reading books, listening to music and drawing pictures.

PUBLICATIONS

PEER REVIEWED PUBLICATIONS
W. Zhou, KM. Chou, X. Liu et al. High immunohistochemical expression of translesion DNA synthesis enzyme polymerase η in head and neck squamous cell carcinoma predicts resistance to Gemcitabine and Cisplatin-Based Chemotherapy.  PLOS ONE Accepted, 2013

P. Ochieng, W. Zhou, E. Hayek, et al.  An Unusual Cause of Itchy Rash with Eosinophilia.  Manuscript submitted to CHEST

K. Zhang, W. Zhou, P. Chu, S. Loria, S. Fujie, Y. Yen.  Exon capturing sequencing reveals frequent Let-7 deletion in adult atypical rhabdoid/teratoid tumors, a case series study.  Manuscriptsubmitted to Cancer.

SF. Lacey, C. La Rosa, T. Kaltcheva, W. Zhou. T. Srivastava, et al, Characterization of immunologic properties of a second HLA-A2 epitope from a granule protease in CML patients and HLA-A2 transgenic mice.  Blood. 2011 Aug 25;118

A. Krishnan, W. Zhou, SF. Lacey, AP. Limaye.  Programmed death-1 receptor and interleukin-10 in liver transplant recipients at high risk for late cytomegalovirus disease.  Transpl Infect Dis. 2010 Aug 1;12(4):363

ER. Manuel, Z. Wang, Z. W. Zhou, C. Li, La Rosa. Intergenic region 3 of modified vaccinia ankara is a functional site for insert gene expression and allows for potent antigen-specific immune responses. Virology. 2010 Aug 1;403(2):155

W. Zhou, S. Fujie, P. Fann, Y. Yen. Carcinoid crisis 24 hours after bland embolization: A case report. Biosci Trends. 2010 Jun;4(3):143-4.

Y. Yen, W. Zhou.  Hepatocellular carcinoma: the search for innovative adjuvant therapies. Review, Oncology. 2009 Dec;23(14):1291,

W. Zhou, J. Longmate, JM Palmer Impact of donor CMV status on viral infection and reconstitution of multifunction CMV-specific T cells in CMV-positive transplant recipients. Blood. 2009 Jun 18;113(25):6465

Z Wang, J Martinez, W Zhou. Modified H5 promoter improves stability of insert genes while maintaining immunogenicity during extended passage of genetically engineered MVA vaccines. Vaccine. 2010 Feb 10;28(6):1547

Z. Wang, W. Zhou, T. Srivastava, A fusion protein of HCMV IE1 exon4 and IE2 exon5 stimulates potent cellular immunity in an MVA vaccine vector. Virology. 2008 Aug 1;377(2):379

W. Zhou, M. Sharma, J. Martinez  Functional characterization of BK virus-specific CD4+ T cells with cytotoxic potential in seropositive adults. Viral Immunol. 2007 Sep;20(3):379

S.F. Lacey, C. La Rosa, W. Zhou, Functional comparison of T cells recognizing cytomegalovirus pp65 and intermediate-early antigen polypeptides in hematopoietic stem-cell transplant and solid organ transplant recipients. J Infect Dis. 2006 Nov 15;194(10):1410

M.C. Sharma, W. Zhou Cross-reactive CTL recognizing two HLA-A*02-restricted epitopes within the BK virus and JC virus VP1 polypeptides are frequent in immunocompetent individuals. Virology. 2006 Jun 20;350(1):12

T. Irei, H. Ohdan, W. Zhou, The persistent elimination of B cells responding to blood group A carbohydrates by synthetic group A carbohydrates and B-1 cell differentiation blockade: novel concept in preventing antibody-mediated rejection in ABO-incompatible transplantation. Blood. 2007 Dec 15;110(13):4567

H. Ohdan, W. Zhou, Y. Tanaka, Evidence of immune tolerance to blood group antigens in a case of ABO-incompatible pediatric liver transplantation. Am J Transplant. 2007 Sep;7(9):2190

T. Onoe, H. Ohdan, D. Tokita, M. Shishida, W. Zhou, Y. Tanaka, H. Hara, K. Ishiyama, H. Mitsuta, K. Ide, T. Asahara, Liver sinusoidal endothelial cells tolerize T cells across MHC barriers in mice. Journal of Immunology, 2004.

M. Ochi, H. Ohdan, H. Mitsuta, T. Onoe, W. Zhou, D. Tokita, H. Hara, Y. Tanaka, T. Asahara, Liver NK cells expressing TNF-related apoptosis-inducing ligand have toxicity against autologous hepatocytes in mice. Hepatology, 2004, 39(5): 1322-1331.

H. Hara, H. Ohdan, W. Zhou, Y. Tanaka, T. Asahara, Construction of ectopic xenogeneic bone marrow structure associated with persistent multi-lineage mixed chimerism by engraftment of rat bone marrow plugs into mouse kidney capsules. Xenotransplantation, 2003,10(3): 259-266.

W. Zhou, H. Ohdan, Y. Tanaka, H. Hara, D. Tokita, T. Onoe, T. Asahara, NOD/SCID mice engrafted with human peripheral blood lymphocytes can be a model for investigating B cells responding to blood group A carbohydrate determinant. Transplantation, 2003,12: 9-18.

NON-PEER REVIEWED PUBLICATIONS
W. Zhou, T. Asahara. Current status of medical insurance in China.  2004. Nihon Geka (Japanese Journal of Surgery).

W. Zhou, Y. Zhang, M. Ge, S. Wang.  Could hepatitis B vaccine prevent hepatic carcinoma in Qidong? Comparison of hepatitis B infection and Exposure to Aflatoxin in Qidong, China.   1999, Nanjing Medical University Campus Journal. (Article in Chinese)

SELECTED CONFERENCE ABSTRACTS
USCAP 2014, poster

W.Zhou, Jayalakshmi Panicker Balakrishna, Violet Ghali.  PHH3 is a reliable marker in grading neuronendocrine tumor

ASCP 2013, poster

W. Zhou, A. Sharabi. Entrapped pancreatic ducts with prominent atypical papillary proliferation and mucin production in a well-differentiated pancreatic neuronendocrine tumor mimicking mixed ductal-endocrine neoplasm: an unusual case and review of 20 pancreatic neuroendocrine tumors.

CAP 2013, poster

W. Zhou, W Miller, N. Theise. Primary Hepatic Poorly Differentiated Neuroendocrine Carcinoma with Intrahepatic Metastasis Presenting as Systemic Opportunistic Infection: a Case Report of Autopsy Findings and Literature Review

CAP 2013, poster

W. Zhou, N. Theise, S. Yuan.  Granular Cell Tumor of Common Bile Duct Inducing Atypical Papillary Hyperplasia of Biliary Epithelium Mimicing Intraductal Papillary Neoplasm of the Bile Duct

USCAP  2013, poster

W. Zhou, K. Chou, X. Liu. et al. High immunohistochemical expression of translesion DNA synthesis enzyme polymerase η in head and neck squamous cell cancer predicts higher resistance to Gemcitabine and Cisplatin-based chemotherapy

ASCP  2012, poster

W. Zhou, A. Sharabi.  Epithelial to mesenchymal transition in 2 cases of primary pancreatic carcinosarcoma: in situ evidences of monoclonal origin of epithelial and mesenchymal components

ASH 2008, poster

W. Zhou, .J Longmate, JM. Palmer. Impact of donor CMV status on viral infection and reconstitution of multifunction CMV-specific T cells in CMV-positive transplant recipients.

World Transplant Congress 2005, oral

W. Zhou, H. Ohdan, T. Asahara.  Calcineurin inhibitors block B-1 cell differentiation: the relevance to immunosuppressive treatment in ABO-incompatible transplantation.

World Transplant Congress 2004, poster

T. Onoe, H. Ohdan, M. Ochi, Y. Tanaka, D. Tokita, W. Zhou, et al.  Multiparameter flow cytometric mixed lymphocyte reaction assay using fluorescent cytoplasmic dye for assessing phenotypic property of T cells responding to allogeneic stimulation.

World Transplant Congress 2004, oral

W. Zhou, H. Ohdan, T. Irei. et al. The persistent elimination of B cells responding to blood group A carbohydrates by synthetic group A carbohydrates and B-1 cell differentiation blockade

World Transplant Congress 2003, poster

Y. Tanaka, H. Ohdan, W. Zhou, et al. Enzyme-linked immunospot assay for detecting cells secreting antibodies against human blood group A epitopes.

World Transplant Congress 2003, poster

H. Hara, H. Ohdan, W. Zhou, et al. Limited engraftment capacity of bone marrow-derived mesenchymal cells in xenogeneic bone marrow transplantation.