PhD – University of Virginia – USA
MD – Hubei Medical University – China
MS – Tongji Medical University – China
INTERESTS IN PATHOLOGY
Tennis, ice skating
Buono KD, Vadlamuri D, Gan Q, Levison SW. Leukemia inhibitory factor is essential for subventricular zone neural stem cell and progenitor homeostasis as revealed by a novel flow cytometric analysis. Dev Neurosci. 2012;34(5):449-62.
Gan Q, Thiébaud P, Thézé N, Jin L, Xu G, Grant P, Owens GK. WDR5, an adaptor protein of histone methyltransferase complexes, is required for smooth muscle differentiation. J Biol Chem. 2011 Jun 17;286(24):21853-64. Epub 2011 Apr 28
Yoshida T, Gan Q, Franke AS, Zhang JF, Chen YE, Majesky MW, Somlyo AV, Owens GK. Smooth and cardiac muscle-selective knockout of Krupple-like factor 4 causes postnatal death and growth retardation. J Biol Chem. 2010 Jul 2;285(27):21175-84. Epub 2010 May 3.
Jin L, Gan Q, Zieba B, Owens GK, Otey Ca, Somlyo AV. The actin associated protein palladin is required for early smooth muscle cell differentiation and altering response following vascular injury. Plos One 2010 Sep 2;285(27):21175-84. Epub 2010 Sep 3.
Deaton RA, Gan Q, Owens GK. Sp1-dependent activation of KLF4 is required for PDGF-BB-induced phenotypic modulation of smooth muscle. Am J Physiol Heart Circ Physiol. 2009 April; 296(4):H1027-37.
Cherepanova OA, Pidkovka NA, Sarmento OF, Yoshida T, Gan Q, Adiguzel E, Bendeck MP, Berliner J, Leitinger N, Owens GK. Oxidized Phospholipids induce type VIII collagen expression and vascular smooth muscle cell migration. Circ Res. 2009 Mar 13;104(5):609-18.
Yoshida T, Gan Q, Owens GK. Kruppel-like factor 4, Elk-1, and histone deacetylases cooperatively suppress smooth muscle cell differentiation markers in response to oxidized phospholipids. Am J Physiol Cell Physiol. 2008 Nov;295(5):C1175-82.
Gan Q, Yoshida T, Li J, Owens GK. Smooth Muscle Cells and Myofibroblasts Employ Distinct Transcriptional Mechanisms for SM a-actin Expression. Cir Res. 2007 Oct 26; 101(9): 83-92
Gan Q, Yoshida T, McDonard O, Owens GK. Concise review: epigenetic mechanisms contribute to pluripotency and cell lineage determination of embryonic stem cells. Stem Cells. 2007 Jan;25(1):2-9.
Yoshida T, Gan Q, Shang Y, Owens GK. Platelet-Derived Growth Factor-BB Represses Smooth Muscle Cell Marker Genes via Changes in Binding of MKL Factors and Histone Deacetylases to their Promoters. Am J Physiol Cell Physiol. 2007 Feb;292(2):C886-95. Epub 2006 Sep 20.
Wang Z, Gan Q, Han S, Liao Y. Effect of Peroxisome Proliferator-activated Receptor- on the VSMCs Apoptosis Induced by Oxidized LDL. ACTA Medical University of Huazhong Science and Technology University, 2006, 35 (5): 596-597, 604.
Wang Z, Gan Q, Han S, Liao Y. The regulation of peroxisome proliferator-activated receptor-γ on apoptotic related genes p53 and bcl-2 in cultured vascular smooth muscle cells. Chinese Journal of Pathology, 2004, 20 (4): 590-594.